drugset / Trial / NCT04933799
IRAK 4 Inhibitor (PF-06650833) in Hospitalized Patients With COVID-19 Pneumonia and Exuberant Inflammation.
RandomizedParallel-groupTriple-blindTreatment
Summary
The aim of the current clinical study is to evaluate the efficacy and safety of inhibition of Interleukin-1 receptor associated kinase 4 (IRAK4) in ameliorating the proinflammatory state and improving outcomes in severe COVID-19.
Timeline
- Start
- 2021-01-06
- Primary completion
- 2022-03-06
- Completion
- 2022-05-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | ZIMLOVISERTIB | Small molecule | 200 mg | Oral |
| Comparator | ZIMLOVISERTIB | Small molecule | 400 mg | Oral |