drugset / Trial / NCT04933799

IRAK 4 Inhibitor (PF-06650833) in Hospitalized Patients With COVID-19 Pneumonia and Exuberant Inflammation.

NCT04933799

Phase 2 Unknown 68 enrolled Giovanni Franchin, M.D, Ph.D Pfizer · collab
RandomizedParallel-groupTriple-blindTreatment

Summary

The aim of the current clinical study is to evaluate the efficacy and safety of inhibition of Interleukin-1 receptor associated kinase 4 (IRAK4) in ameliorating the proinflammatory state and improving outcomes in severe COVID-19.

Timeline

Start
2021-01-06
Primary completion
2022-03-06
Completion
2022-05-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator ZIMLOVISERTIB Small molecule 200 mg Oral
Comparator ZIMLOVISERTIB Small molecule 400 mg Oral

Indications