drugset / Trial / NCT04936529

A Study of a Vaccine in Combination With β-glucan and GM-CSF in People With Neuroblastoma

NCT04936529

Phase 2 Recruiting 286 enrolled Memorial Sloan Kettering Cancer Center
RandomizedFactorialOpen-labelTreatment

Summary

The purpose of the study is to explore the combination of a bivalent vaccine, a sugar called beta-glucan (β-glucan), and a protein called granulocyte-macrophage colony stimulating factor (GM-CSF) as an effective treatment for people with high-risk neuroblastoma that is in complete remission. The combination may be effective because the different parts of the treatment work to strengthen the immune system's response against cancer cells in different ways.

Timeline

Start
2021-08-02
Primary completion
2027-06-15
Completion
2027-06-15

Drugs

EvaluationDrugModalityDoseRoute
Subject OBI-821 Other / unclassified
Subject sargramostim Protein / enzyme biologic 250 ug/m2

Indications