drugset / Trial / NCT04938102

Role of EndoFLIP in the Diagnostic Paradigm of Esophagogastric Junction Outflow Obstruction

NCT04938102

RandomizedParallel-groupSingle-blindDiagnostic

Summary

The aim of this project is to identify if EndoFLIP can categorize and change the diagnosis in patients with EGJOO and if categorization with EndoFLIP can predict the response to treatment with botulinum toxin at 12 weeks post procedure. Our hypothesis is that there will be greater symptom resolution in the treatment versus control in the abnormal DI category. In addition, we hypothesize there will be less symptom resolution in the control group with an abnormal DI as compared to those with a normal DI who also receive no treatment.

Timeline

Start
2022-07
Primary completion
2023-07
Completion
2024-10-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator Botulinum toxin type A Protein / enzyme biologic 100 iu Other

Indications