drugset / Trial / NCT04942340
Turning Dexmedetomidine Into a Powerful Anesthetic That Can be Rapidly and Completely Reversed
RandomizedParallel-groupSingle-blindTreatment
Summary
In this study, the investigators will explore Atipamezole \& caffeine's ability to facilitate the emergence from anesthesia. Each subject will visit UChicago 4 times. The first time for informed consent. The second time for a complete physical exam to ensure that the subjects are healthy. Then there are 2 sedation sessions. Subjects get an honorarium for each sedation session.
Timeline
- Start
- 2023-05
- Primary completion
- 2026-04
- Completion
- 2026-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Atipamezole | Small molecule | 2 g/kg | Intravenous |
| Comparator | Caffeine | Small molecule | 15 mg/kg | Intravenous |
| Comparator | Dexmedetomidine | Other / unclassified | 15 mg/kg | Intravenous |
Indications
No indication recorded.