drugset / Trial / NCT04956068
PIPAC for Peritoneal Metastases
Non-randomizedParallel-groupOpen-labelTreatment
Summary
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel drug delivery system that allows the direct application of chemotherapeutic agents into the peritoneal cavity. It boosts improved distribution, enhanced tissue uptake and repeatability using minimally invasive access. It was devised to palliate the local symptoms of extensive peritoneal metastases (PM) in patients who are not amenable to curative surgery. This study is to determine safety and feasibility of PIPAC in patients with PM from Gastrointestinal (GI) cancer, Hepato-Pancreato-Biliary (HPB) cancer, and other rare malignancies.
Timeline
- Start
- 2021-05-20
- Primary completion
- 2026-11
- Completion
- 2026-11
Outcome
Outcome not reported
Stopped (Business): “Awaiting further funding.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cisplatin | Other / unclassified | — | Other |
| Subject | Doxorubicin | Other / unclassified | — | Other |
| Subject | Oxaliplatin | Small molecule | — | Other |