drugset / Trial / NCT04962022
Drug-Drug Interaction Study Assessing Effect of Itraconazole on PF-07321332/Ritonavir in Healthy Participants
Non-randomizedCrossoverOpen-labelBasic science
Summary
The purpose of this study is to estimate the effect of a strong inhibitor of CYP3A4 (itraconazole) on the pharmacokinetics (PK) of PF-07321332/ritonavir in healthy participants.
Timeline
- Start
- 2021-07-20
- Primary completion
- 2021-09-30
- Completion
- 2021-09-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Itraconazole | Small molecule | — | Oral |
| Subject | Nirmatrelvir | Small molecule | — | Oral |
| Subject | Ritonavir | Other / unclassified | — | Oral |
Indications
No indication recorded.