drugset / Trial / NCT04962451
Comparison of the Efficacy of Ticagrelor Combined With ASA to ASA Alone in Patients With Stroke
RandomizedParallel-groupDouble-blindTreatment
Summary
Cerebrovascular disease is the main cause of death and severe long-term disability worldwide. Antiplatelet drugs are the main drugs for ischemic stroke and TIA. Cyclooxygenase inhibitor acetylsalicylic acid (ASA) has always been the most widely studied antiplatelet therapy. The studies of acrates of aliscon body evaluated the efficacy and safety of ticagrelor monotherapy in preventing major vascular events in patients with AIS or TIA. The results showed that the number of patients with endpoint events in ticagrelor group was less than that in ASA group, However, it has not been proved that ticagrelor monotherapy is better than ASA. The purpose of this study is to prove that ticagrelor is better than ASA.
Timeline
- Start
- 2017-09-01
- Primary completion
- 2019-09-30
- Completion
- 2019-10-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ticagrelor | Small molecule | 90 mg | — |
| Background | Aspirin | Small molecule | 75 mg | — |
| Background | Aspirin | Small molecule | 100 mg | — |