drugset / Trial / NCT04962724
A Study to Evaluate the Absorption, Metabolism, and Excretion and Absolute Bioavailability of Xevinapant in Healthy Male Participants
Non-randomizedParallel-groupOpen-labelBasic science
Summary
The purpose of the study is to determine absorption, metabolism, and excretion of a single oral dose of \[14C\]-xevinapant. This information will enable assessment of absorption and clearance mechanisms of \[14C\]-xevinapant as well as identify metabolites. In addition, the study will allow to determine absolute bioavailability of xevinapant and understand its intravenous pharmacokinetics.
Timeline
- Start
- 2021-08-02
- Primary completion
- 2021-11-09
- Completion
- 2021-11-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Xevinapant | Small molecule | 100 ug | Oral |
| Subject | Xevinapant | Small molecule | 200 mg | Oral |
Indications
No indication recorded.