drugset / Trial / NCT04964518

A Study of APG-2575 in Combination With Azacitidine in Patients With Acute Myeloid Leukemia (AML)

NCT04964518

Phase 1/2 Unknown 24 enrolled Ascentage Pharma Group Inc.
NaSequentialOpen-labelTreatment

Summary

This is a Phase Ib/II, open-label, multi-center study evaluating the safety, tolerability, efficacy and PK of APG-2575 in combination with Azacitidine in the patients with AML/MPAL or MDS/CMML. The study consists of dose escalation (Part I) and dose expansion phase (Part II)

Timeline

Start
2021-07-30
Primary completion
2024-07-30
Completion
2024-10-30

Drugs

EvaluationDrugModalityDoseRoute
Subject APG-2575 Small molecule 200 mg
Background Azacitidine Other / unclassified