Protective Effect of Sivelestat Sodium on ARDS in Patients With Sepsis

Summary

Sivelestat sodium has been approved for use in patients with SIRS and ALI, but whether it can protect patients with sepsis from developing ARDS remains unknown.The aim of this study was to determine whether sivelestat sodium has a protective effect on ARDS in patients with sepsis.

Timeline

Start

2021-10-11

Primary completion

2023-09-30

Completion

2023-10-30

Publications

• Ma S, Li C, Gao Z, Xie J, Qiu H, Yang Y, Liu L. Effects of intravenous sivelestat sodium on prevention of acute respiratory distress syndrome in patients with sepsis: study protocol for a double-blind multicentre randomised controlled trial. BMJ Open. 2023 Sep 13;13(9):e074756. doi: 10.1136/bmjopen-2023-074756.

Drugs

Indications