drugset / Trial / NCT04981457
Comparative Study Between Combined Vaginal Misoprostol
RandomizedParallel-groupSingle-blindTreatment
Summary
"Comparative study between Combined Vaginal Misoprostol with Isosorbide-5-Mononitrate
Timeline
- Start
- 2021-03-02
- Primary completion
- 2021-09
- Completion
- 2021-10
Publications
- Background Arteaga-Troncoso G, Villegas-Alvarado A, Belmont-Gomez A, Martinez-Herrera FJ, Villagrana-Zesati R, Guerra-Infante F. Intracervical application of the nitric oxide donor isosorbide dinitrate for induction of cervical ripening: a randomised controlled trial to determine clinical efficacy and safety prior to first trimester surgical evacuation of retained products of conception. BJOG. 2005 Dec;112(12):1615-9. doi: 10.1111/j.1471-0528.2005.00760.x.
- Background Carlsson I, Breding K, Larsson PG. Complications related to induced abortion: a combined retrospective and longitudinal follow-up study. BMC Womens Health. 2018 Sep 25;18(1):158. doi: 10.1186/s12905-018-0645-6.
- Background Kim C, Barnard S, Neilson JP, Hickey M, Vazquez JC, Dou L. Medical treatments for incomplete miscarriage. Cochrane Database Syst Rev. 2017 Jan 31;1(1):CD007223. doi: 10.1002/14651858.CD007223.pub4.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Isosorbide Mononitrate | Other / unclassified | 20 mg | Oral |
| Comparator | Misoprostol | Other / unclassified | 800 ug | Intravenous |