drugset / Trial / NCT04987775
GWICTIC: NAC Mechanistic Study in Gulf War Veterans
Phase 0
Recruiting
170 enrolled
Nova Southeastern University
Boston University · collabRTI International · collabWeill Medical College of Cornell University · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
This mechanistic study will test if NAC affects chronic oxidative stress and depletion of antioxidants in GWI participants. Blood specimen collection and neuroimaging will be used to determine whether NAC affects serum glutathione (GSH) concentration and oxidative stress in the CNS when compared to placebo.
Timeline
- Start
- 2023-11-30
- Primary completion
- 2026-04
- Completion
- 2026-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | N-acetylcysteine | Small molecule | 900 mg | — |