Effect of Tramadol on Postoperative Sore Throat After General Anesthesia

Summary

Post operative sore throat after general anesthesia with endotracheal intubation is a common problem causing dissatisfaction and discomfort to the patients. The investigators want to study the effect of tramadol on postoperative sore throat in general anesthesia with endotracheal intubation.

Timeline

Start

2021-09-10

Primary completion

2023-11-01

Completion

2024-07

Publications

• Background Hu B, Bao R, Wang X, Liu S, Tao T, Xie Q, Yu X, Li J, Bo L, Deng X. The size of endotracheal tube and sore throat after surgery: a systematic review and meta-analysis. PLoS One. 2013 Oct 4;8(10):e74467. doi: 10.1371/journal.pone.0074467. eCollection 2013.
• Background El-Boghdadly K, Bailey CR, Wiles MD. Postoperative sore throat: a systematic review. Anaesthesia. 2016 Jun;71(6):706-17. doi: 10.1111/anae.13438. Epub 2016 Mar 28.
• Background Tekelioglu UY, Apuhan T, Akkaya A, Demirhan A, Yildiz I, Simsek T, Gok U, Kocoglu H. Comparison of topical tramadol and ketamine in pain treatment after tonsillectomy. Paediatr Anaesth. 2013 Jun;23(6):496-501. doi: 10.1111/pan.12148. Epub 2013 Mar 23.
• Background Lin BF, Ju DT, Cherng CH, Hung NK, Yeh CC, Chan SM, Wu CT. Comparison between intraoperative fentanyl and tramadol to improve quality of emergence. J Neurosurg Anesthesiol. 2012 Apr;24(2):127-32. doi: 10.1097/ANA.0b013e31823c4a24.
• Su Z, Huang J, Xu X, Yang B, Lv X, Zhang S, Wang X, Chen E, Xu Y, Lin Y, Huang X, Su Y, Li L, Yin Y, Guo Z, Tong L, Huang M, Xu X. Tramadol and postoperative sore throat after tracheal intubation in thyroid surgery - a randomized controlled trial. BMC Anesthesiol. 2025 Dec 22;25(1):610. doi: 10.1186/s12871-025-03487-z.

Drugs

Indications

No indication recorded.