drugset / Trial / NCT04991948

Study of Pembrolizumab Treatment After CYAD-101 With FOLFOX Preconditioning in Metastatic Colorectal Cancer

NCT04991948

Phase 1 Recruiting 34 enrolled Celyad Oncology SA Merck Sharp & Dohme LLC · collab
NaSequentialOpen-labelTreatment

Summary

The purpose of the CYAD-101-002 study is to assess the safety and clinical activity of CYAD-101 in patients with unresectable metastatic colorectal cancer administered concurrently with FOLFOX chemotherapy, followed by pembrolizumab treatment.

Timeline

Start
2021-11-22
Primary completion
2023-08-21
Completion
2038-05-25

Drugs

EvaluationDrugModalityDoseRoute
Subject CYAD-101 Cell therapy
Subject Pembrolizumab Monoclonal antibody
Background Leucovorin Small molecule
Background Oxaliplatin Small molecule
Background fluorouracil Small molecule

Indications