drugset / Trial / NCT04999137
Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Africa
Phase 2
Unknown
60 enrolled
Liverpool School of Tropical Medicine
Infectious Diseases Institute, Uganda · collabUniversity of Copenhagen · collabUniversity of Liverpool · collabWalimu · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
Open-label phase 2a Randomized Controlled Trial (RCT) assessing the pharmacokinetics of two different doses of intravenous vitamin C given alongside vitamin B1 in adult medical patients with sepsis and hypotension.
Timeline
- Start
- 2021-09-01
- Primary completion
- 2021-12-29
- Completion
- 2021-12-29
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Thiamine | Other / unclassified | 200 mg | Intravenous |
| Subject | Vitamin C | Other / unclassified | 1.5 g | Intravenous |
| Subject | Vitamin C | Other / unclassified | 3 g | Intravenous |