drugset / Trial / NCT05004636

Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Post-operative Pain Relief and Decrease Opioid Consumption: a Prospective Randomized Controlled Trial

NCT05004636

Completed 119 enrolled Wayne State University
RandomizedParallel-groupTriple-blindSupportive care

Summary

The purpose of this study is to determine whether the addition of magnesium to bupivacaine for the post-operative adductor canal blocks (ACB) can decrease opioid consumption and improve pain management for patients after same-day discharge total knee arthroplasty (TKA). The investigators will assess whether the addition of magnesium will decrease visual analog scale (VAS) pain scores, decrease post-operative total opioid consumption (oral morphine equivalents), decrease the incidence of post-operative nausea and vomiting (PONV), and improve patient satisfaction in comparison to when magnesium is not administered.

Timeline

Start
2020-08-05
Primary completion
2021-05-29
Completion
2021-05-29

Drugs

EvaluationDrugModalityDoseRoute
Subject Magnesium Sulfate Other / unclassified 150 mg Other
Background Bupivacaine Other / unclassified 0.25 % Other
Background Bupivacaine Other / unclassified 30 ml Other

Indications

No indication recorded.