drugset / Trial / NCT05005312
Study to Estimate the Effects of Hepatic Impairment on the Pharmacokinetics (PK) of PF-07321332
Non-randomizedParallel-groupOpen-labelBasic science
Summary
The study is to estimate the effect of hepatic impairment on the plasma PK of PF-07321332/ritonavir. Findings from this study will be used to develop dosing recommendations so that the dose and/or dosing interval may be adjusted appropriately in the presence of hepatic impairment.
Timeline
- Start
- 2021-08-31
- Primary completion
- 2021-12-07
- Completion
- 2021-12-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nirmatrelvir | Small molecule | — | — |
| Background | Ritonavir | Other / unclassified | — | — |
Indications
No indication recorded.