drugset / Trial / NCT05014685

PPI-amoxicillin for H. Pylori Treatment

NCT05014685

Phase 4 Unknown 732 enrolled Shanghai Zhongshan Hospital
RandomizedFactorialOpen-labelTreatment

Summary

This randomized controlled clinical trial will identify the additional benefit of bismuth or metronidazole in proton pump inhibitor-amoxicillin-containing therapy for Helicobacter pylori first-line treatment. The completion of this trial will expand new therapy for the treatment of Helicobacter pylori, which can not only ensure clinical efficacy, but also reduce the use of antibiotics.

Timeline

Start
2021-08-20
Primary completion
2022-12-30
Completion
2022-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Amoxicillin Other / unclassified 1 g
Subject Bismuth Potassium Citrate Unknown 0.6 g
Subject Metronidazole Small molecule 0.4 g
Subject Rabeprazole Small molecule 20 mg