drugset / Trial / NCT05020444

TriPRIL CAR T Cells in Multiple Myeloma

NCT05020444 ↗

Phase 1 Recruiting 18 enrolled Massachusetts General Hospital
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This research study involves the study of TriPRIL CAR T Cells for treating people with relapsed or refractory multiple myeloma and to understand the side effects when treated with TriPRIL CAR T Cells. This research study involves the study drugs:. * TriPRIL CAR T Cells * Fludarabine and Cyclophosphamide: Standardly used chemotherapy drugs as part of lymphodepleting process

Timeline

Start
2021-10-05
Primary completion
2028-02-24
Completion
2028-02-24

Drugs

EvaluationDrugModalityDoseRoute
Subject TriPRIL CAR T Cells Cell therapy — Intravenous
Background Cyclophosphamide Other / unclassified — Intravenous
Background Fludarabine Small molecule — Intravenous

Indications