drugset / Trial / NCT05032924

The Clinical and Biological Effect of ESWT With Combined PRP Therapy on Rotator Cuff Lesions

NCT05032924

Unknown 50 enrolled Chang Gung Memorial Hospital
RandomizedParallel-groupTriple-blindTreatment

Summary

Through the investigators previous study of the effect of transient increased cellular permeability after ESWT, combined ESWT and PRP may have better effect on the treatment of rotator cuff lesions. The investigators intend to conduct a prospective double blind randomized control study on the treatment effect of combined ESWT and PRP therapy for rotator cuff lesions without complete tearing. Constant Score, VAS and data from peripheral blood will be measured for the effectiveness evaluation. Shoulder MRI will be followed-up one year after ESWT. The investigators hypothesize that combined ESWT and PRP will be more effective for rotator cuff lesions.

Timeline

Start
2021-08-02
Primary completion
2024-07-31
Completion
2024-07-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Platelet Rich Plasma Other / unclassified 2.5 ml Other
Subject Sodium Hyaluronate Other / unclassified 2.5 ml Other
Subject Sodium Hyaluronate Other / unclassified 25 mg Other

Indications