drugset / Trial / NCT05038839

Cabozantinib and Pamiparib for the Treatment of Advanced of Refractory Solid Tumors

NCT05038839

Phase 1 Completed 44 enrolled M.D. Anderson Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

This phase I trial finds the best dose and side effects of cabozantinib and pamiparib in treating patients with solid tumors that have spread to other places in the body (advanced) or does not respond to treatment (refractory). Cabozantinib and pamiparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2022-02-09
Primary completion
2026-05-05
Completion
2026-05-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Cabozantinib Small molecule Oral
Subject Pamiparib Small molecule Oral