drugset / Trial / NCT05039736
A Phase II Study to Evaluate the Effects of Sequential Therapy With the Anti c-MET/VEGFR Tyrosine Kinase Inhibitor (TKI), Cabozantinib, Followed by an Anti-PD-1 Antibody (Nivolumab) in Patients With Advanced HCC Who Progressed on First-line Therapy
RandomizedSingle-groupOpen-labelTreatment
Summary
The purpose of this clinical research study is to learn about the safety and effectiveness of cabozantinib and nivolumab in people with hepatocellular carcinoma (HCC).
Timeline
- Start
- 2023-02-24
- Primary completion
- 2023-05-03
- Completion
- 2023-05-03
Outcome
Outcome not reported
Stopped (Enrollment): “0 participants accrued”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cabozantinib | Small molecule | — | Oral |
| Subject | Nivolumab | Monoclonal antibody | — | Intravenous |