drugset / Trial / NCT05054374

A Study of Mirdametinib on Its Own or in Combination With Fulvestrant in People With Solid Tumor Cancer

NCT05054374

Phase 1/2 Completed 6 enrolled Memorial Sloan Kettering Cancer Center
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study to find out whether mirdametinib is a safe treatment for people with advanced solid tumor cancer that has certain mutations. Researchers will look at whether mirdametinib on its own or in combination with the drug fulvestrant is a safe treatment that causes few or mild side effects in people with advanced solid tumor cancer.

Timeline

Start
2021-09-14
Primary completion
2023-10-26
Completion
2023-10-26

Drugs

EvaluationDrugModalityDoseRoute
Subject Mirdametinib Small molecule 2 mg Oral
Subject Mirdametinib Small molecule 3 mg Oral
Subject Mirdametinib Small molecule 4 mg Oral
Subject Mirdametinib Small molecule 6 mg Oral
Subject Mirdametinib Small molecule 8 mg Oral
Background Fulvestrant Small molecule