drugset
drugset / Trial / NCT05064202

Unloading in Heart Failure Cardiogenic Shock

NCT05064202 ↗

Not yet recruiting 456 enrolled Amsterdam UMC, location VUmc Abiomed Inc. · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this research study is to evaluate whether timely and aggressive temporary Mechanical Circulatory Support (tMCS) through the Impella 5.5® in patients with acute decompensated heart failure complicated by cardiogenic shock (ADHF-CS) has the potential to reduce the HF-CS related clinical events compared to the current standard of care.

Timeline

Start
2023-10-01
Primary completion
2027-10-01
Completion
2028-07-01

Drugs

EvaluationDrugModalityDoseRoute
Background Dobutamine Small molecule — —
Background Dopamine Small molecule — —
Background Enoximone Small molecule — —
Background Milrinone Small molecule — —

Indications

cardiogenic shock