drugset / Trial / NCT05069246

The Clinical Assessment of Nigella Sativa Oil vs Chlorohexidine as a Therapeutic Aid for Gingivitis, Effect on Gingival IL-6 and IL-18 and Antimicrobial Efficacy.

NCT05069246

Phase 2 Completed 37 enrolled Ishrat Rahman
RandomizedParallel-groupDouble-blindTreatment

Summary

A double-blind randomized clinical trial was conducted for 14 days with 37 systemically healthy patients having chronic generalized gingivitis. The current study was designed to investigate the anti-inflammatory and antimicrobial efficacy of Nigella Sativa oil compared with chlorohexidine; assessing clinical parameters and gingival interleukin 6 (IL6) and interleukin 18 (IL18) levels and supra-gingival plaque analysis.

Timeline

Start
2020-12-08
Primary completion
2020-12-24
Completion
2021-02-28

Drugs

EvaluationDrugModalityDoseRoute
Comparator Chlorhexidine Small molecule 10 ml Oral

Indications