drugset / Trial / NCT05072262

DSAEK/DMEK and Cystoid Macular Edema - the Role for Topical NSAIDs (Nepafenac) (DMEC)

NCT05072262

Phase 4 Recruiting 300 enrolled Oslo University Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

The DMEC trial is a randomized clinical two-arm trial comparing inflammation and cystoid macular edema for the medication regimens postoperative topical NSAIDs and steroids to only postoperative topical steroids in patients undergoing corneal endothelial transplantations (DSAEK or DMEK).

Timeline

Start
2022-11-25
Primary completion
2024-06
Completion
2026-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Nepafenac Other / unclassified 3 mg/ml Topical
Background Dexamethasone Small molecule 1 mg/ml Topical

Indications

No indication recorded.