drugset / Trial / NCT05076877
A Study of Lazertinib (JNJ-73841937) in Healthy Participants
NaSingle-groupOpen-labelBasic science
Summary
The purpose of this study is to evaluate the effect of steady-state concentrations of lazertinib on the single-dose pharmacokinetics (PK) of probe substrates (midazolam, rosuvastatin, and metformin) in healthy adult participants.
Timeline
- Start
- 2021-09-17
- Primary completion
- 2022-02-10
- Completion
- 2022-02-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lazertinib | Small molecule | — | Oral |
| Subject | Metformin | Small molecule | — | Oral |
| Subject | Midazolam | Small molecule | — | Oral |
| Subject | Rosuvastatin | Small molecule | — | Oral |
Indications
No indication recorded.