drugset / Trial / NCT05087914
Novel Non-opioid Post-surgical Pain Treatment in Females
Phase 2
Withdrawn
Northwestern University
National Institutes of Health (NIH) · collabNorthwestern Medical Group · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This study aims to determine if treatment with Carbidopa/Levodopa and Naproxen in females (biological sex) with acute pain after a bunionectomy or toe fusion (24hrs, 48hrs and 5 days) will reduce pain when compared with females receiving Placebo and Naproxen.
Timeline
- Start
- 2021-11-01
- Primary completion
- 2023-12-30
- Completion
- 2024-01-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Levodopa | Small molecule | 25 mg | Oral |
| Subject | Levodopa | Small molecule | 100 mg | Oral |
| Background | Naproxen | Small molecule | 250 mg | Oral |
Indications
No indication recorded.