drugset / Trial / NCT05090566

MagnetisMM-4: Umbrella Study of Elranatamab (PF-06863135) in Combination With Anti-Cancer Treatments in Multiple Myeloma

NCT05090566

Phase 2 Terminated 46 enrolled Pfizer
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to determine the Recommended Phase 2 Dose and clinical benefit of elranatamab in combination with other anti-cancer therapies in participants with multiple myeloma.

Timeline

Start
2021-10-27
Primary completion
2025-02-13
Completion
2026-03-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule
Subject Elranatamab Monoclonal antibody
Subject Lenalidomide Other / unclassified
Subject Nirogacestat Small molecule

Indications