drugset / Trial / NCT05092841

A Study to Assess the Efficacy and Safety of PXT3003 in Charcot-Marie-Tooth Type 1A

NCT05092841

Phase 3 Completed 176 enrolled Tasly GeneNet Pharmaceuticals Co., Ltd
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This is a randomized, double-blind, placebo-controlled and multicenter 3 phase trial evaluating the therapeutic effect and safety of CMT1A by PXT3003. This double-blind study will assess in parallel groups 1 dose of PXT3003 compared to Placebo in CMT1A patients treated for 15 months.

Timeline

Start
2021-09-28
Primary completion
2024-03-18
Completion
2024-03-18

Drugs

EvaluationDrugModalityDoseRoute
Subject Baclofen Small molecule Oral
Subject Naltrexone Small molecule Oral
Subject Sorbitol Small molecule Oral