drugset / Trial / NCT05093205
STUDY TO EVALUATE THE EFFECT OF PF-06882961 ON SINGLE DOSE ATORVASTATIN, MEDAZOLAM AND ORALCONTRACEPTIVE PHARMACOKINETICS IN HEALTHY ADULT PARTICIPANTS
Non-randomizedSequentialOpen-labelBasic science
Summary
The purpose of this study is to characterize the effect of PF-06882961, administered at 2 steady-state dose levels, on the PK of single doses of atorvastatin (20 mg) or midazolam (5 mg), administered separately, in healthy adult male and female participants (Part A), or an OC in healthy PM female participants (Part B).
Timeline
- Start
- 2021-10-25
- Primary completion
- 2022-07-06
- Completion
- 2022-07-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Atorvastatin | Small molecule | 20 mg | Oral |
| Subject | Danuglipron | Small molecule | — | — |
| Subject | Levonorgestrel | Small molecule | 0.15 mg | Oral |
| Subject | Midazolam | Small molecule | 5 mg | Oral |
| Subject | ethinyl estradiol | Small molecule | 0.03 mg | Oral |
Indications
No indication recorded.