drugset / Trial / NCT05108428
Adaptive Radiation for Locally Advanced Rectal Adenocarcinoma
Phase 0
Active not recruiting
20 enrolled
H. Lee Moffitt Cancer Center and Research Institute
Natera, Inc. · collabViewray Inc. · collab
NaSingle-groupOpen-labelTreatment
Summary
The purpose of the study is to determine the feasibility of using magnetic resonance imaging (MRI)-guided adaptive chemoradiation therapy to improve response to treatment.
Timeline
- Start
- 2021-12-23
- Primary completion
- 2023-10-09
- Completion
- 2026-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Capecitabine | Small molecule | 825 mg/m2 | Oral |
| Background | Leucovorin | Small molecule | 400 mg/m2 | Intravenous |
| Background | Oxaliplatin | Small molecule | 85 mg/m2 | Intravenous |
| Background | fluorouracil | Small molecule | 400 mg/m2 | Intravenous |
| Background | fluorouracil | Small molecule | 2400 mg/m2 | Intravenous |