drugset / Trial / NCT05110469

Comparison of MgSO4 Versus Meperidine for Prevention of Shivering During Spinal Anesthesia

NCT05110469

Phase 4 Completed 100 enrolled AnestesiaR
RandomizedParallel-groupQuadruple-blindPrevention

Summary

This was a double-blind randomized interventional study of 100 patients divided into two groups. Group M received MgSO4 30 mg/kg, and group P received meperidine 0.5 mg/kg intravenously in 100 ml of 0.9% NaCl before undergoing spinal anesthesia. Participants were non-pregnant patients between 18-65 years of age, belonging to the American Society of Anesthesiologist physical status I or II. Shivering was regarded as significant if it occurred at grade 3 or 4. Data of patient characteristics, shivering degree, tympanic membrane temperature, vital sign, and side effects were recorded.

Timeline

Start
2021-02-01
Primary completion
2021-06-30
Completion
2021-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Magnesium Sulfate Other / unclassified 30 mg/kg Intravenous
Subject Meperidine Unknown 0.5 mg/kg Intravenous