drugset / Trial / NCT05110469
Comparison of MgSO4 Versus Meperidine for Prevention of Shivering During Spinal Anesthesia
RandomizedParallel-groupQuadruple-blindPrevention
Summary
This was a double-blind randomized interventional study of 100 patients divided into two groups. Group M received MgSO4 30 mg/kg, and group P received meperidine 0.5 mg/kg intravenously in 100 ml of 0.9% NaCl before undergoing spinal anesthesia. Participants were non-pregnant patients between 18-65 years of age, belonging to the American Society of Anesthesiologist physical status I or II. Shivering was regarded as significant if it occurred at grade 3 or 4. Data of patient characteristics, shivering degree, tympanic membrane temperature, vital sign, and side effects were recorded.
Timeline
- Start
- 2021-02-01
- Primary completion
- 2021-06-30
- Completion
- 2021-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Magnesium Sulfate | Other / unclassified | 30 mg/kg | Intravenous |
| Subject | Meperidine | Unknown | 0.5 mg/kg | Intravenous |