drugset / Trial / NCT05118204
Randomized Trial of Buprenorphine Microdose Inductions During Hospitalization
Phase 4
Terminated
23 enrolled
Montefiore Medical Center
National Institute on Drug Abuse (NIDA) · collabWake Forest University · collabWeill Medical College of Cornell University · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
Investigators will test a novel protocol for starting BUP (buprenorphine-naloxone) treatment. The BUP microdose induction protocol has participants start very low doses of BUP without stopping other opioids that they are taking. The treatment as usual (TAU) has participants stop other opioids and experience opioid withdrawal before starting BUP. Investigators propose to test BUP microdose inductions vs. TAU in a randomized controlled trial.
Timeline
- Start
- 2022-09-29
- Primary completion
- 2024-10-23
- Completion
- 2025-04-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Buprenorphine | Other / unclassified | 8 mg | — |