Efficacy of CHX Cloths Versus CHX Soaps for Bathes Before Orthopedic Surgery

Summary

Surgical site infections (SSI) in orthopedic surgery are rare events but associated with great morbidity as well as a significant additional cost. The World Health Organization (WHO) recently carried out meta-analyzes on all the existing prophylactic measures and could not rule on the use of chlorhexidine (CHX) cloths due to the low number of studies available. CHX cloths could actually benefit patients for whom preoperative showering is not possible, whether in emergency or trauma settings due to pain-induced functional impotence. A randomized controlled clinical study aimed at evaluating the in vivo microbiological efficacy of CHX cloths in a population of orthopedic surgery patients while evaluating the psycho-social determinants of adherence to a new preoperative preparation technique seems essential.

Timeline

Start

2021-11-15

Primary completion

2023-05-30

Completion

2023-05-30

Publications

• Gallouche M, Rubens-Duval B, Boisset S, Margotton M, Caspar Y, Le Marechal M, Bosson JL, Astagneau P, Gauchet A, Landelle C. Evaluation of microbiological efficacy of 2% chlorhexidine gluconate cloths versus 4% chlorhexidine gluconate soap for preoperative preparation/shower in total joint arthroplasty: a single-centre randomised controlled trial. Antimicrob Resist Infect Control. 2025 Nov 25;14(1):143. doi: 10.1186/s13756-025-01661-z.

Drugs

Indications

No indication recorded.