drugset / Trial / NCT05123053
Firdapse for Post-BOTOX Vocal Weakness
NaSingle-groupOpen-labelTreatment
Summary
Botox injections into the thyroarytenoid muscle are a predictable and effective treatment for SD, but typically result in transient symptoms of voice weakness and breathiness during the first 2-3 weeks after injection. Investigators hypothesize that voice weakness and breathiness after Botox treatment can be alleviated using amifampridine.
Timeline
- Start
- 2021-10-28
- Primary completion
- 2025-05-27
- Completion
- 2025-09-23
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Amifampridine | Small molecule | 10 mg | — |
Indications
No indication recorded.