drugset / Trial / NCT05123365

An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms

NCT05123365

Phase 1/2 Recruiting 27 enrolled University of California, Irvine
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a phase I/II study evaluating the optimal dose of N-acetylcysteine (N-AC) in patients with myeloproliferative neoplasms (MPN).

Timeline

Start
2022-01-03
Primary completion
2026-11-15
Completion
2026-11-15

Drugs

EvaluationDrugModalityDoseRoute
Subject N-acetylcysteine Small molecule 600 mg Oral
Subject N-acetylcysteine Small molecule 1200 mg Oral
Subject N-acetylcysteine Small molecule 1800 mg Oral