drugset / Trial / NCT05132595
Esketamine vs. Ketorolac for Prevention of Postoperative Pain and Cognitive Dysfunction After Total Knee Arthroplasty
RandomizedParallel-groupTriple-blindPrevention
Summary
Purpose: To compare esketamine and ketorolac separately and in combination to prevent postoperative pain and cognitive dysfunction after total knee arthroplasty
Timeline
- Start
- 2021-11-30
- Primary completion
- 2022-07-15
- Completion
- 2022-07-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Esketamine | Other / unclassified | 0.2 mg/kg | Intravenous |
| Comparator | Esketamine | Other / unclassified | 0.4 mg/kg | Intravenous |
| Comparator | Ketorolac | Other / unclassified | 0.2 mg/kg | Intravenous |
| Comparator | Ketorolac | Other / unclassified | 0.4 mg/kg | Intravenous |