drugset / Trial / NCT05140694

Effect of Empagliflozin and Dulaglutide on MAFLD in Patients With T2D

NCT05140694

Phase 4 Unknown 135 enrolled Seoul National University Bundang Hospital
RandomizedParallel-groupDouble-blindTreatment

Summary

The co-administration of SGLT2 inhibitor and GLP-1 receptor agonist would be safe and effective on glycemic control in subjects with type 2 diabetes mellitus and MAFLD better than empagliflozin or dulaglutide alone. The SGLT2 inhibitor and GLP-1 receptor agonist would be safe and effective on fatty liver disease in subjects with type 2 diabetes mellitus and MAFLD.

Timeline

Start
2023-12-01
Primary completion
2024-06-30
Completion
2025-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Dulaglutide Peptide 0.75 mg Subcutaneous
Subject Empagliflozin Small molecule 10 mg Oral