drugset / Trial / NCT05141682

Oral Azacitidine for the Treatment of Relapsed or Refractory T-cell Large Granular Lymphocytic Leukemia

NCT05141682 ↗

Phase 1/2 Active not recruiting 11 enrolled Jonathan Brammer Bristol-Myers Squibb · collab
NaSingle-groupOpen-labelTreatment

Summary

This phase I/II trial studies the best dose, possible benefits and/or side effects of oral azacitidine in treating patients with T-cell large granular lymphocytic leukemia that has come back (relapsed) or has not responded to previous treatment (refractory). Chemotherapy drugs, such as azacitidine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

Timeline

Start
2022-06-29
Primary completion
2026-02-19
Completion
2026-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Azacitidine Other / unclassified — Oral