drugset / Trial / NCT05142865

Camrelizumab Combined With Chemotherapy and Apatinib for Extrapulmonary Neuroendocrine Carcinomas

NCT05142865 ↗

Phase 2 Unknown 30 enrolled Huazhong University of Science and Technology
NaSingle-groupOpen-labelTreatment

Summary

This is an open-label,single-arm, phase II exploratory study that evaluates the efficacy and safety of Camrelizumab combined with Chemotherapy (carboplatin or cisplatin + etoposide)and Apatinib as First Line treatment in Advanced or Metastatic Extrapulmonary Neuroendocrine Carcinomas(EP-NEC)

Timeline

Start
2022-01-14
Primary completion
2024-01-14
Completion
2024-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Camrelizumab Monoclonal antibody 200 mg Intravenous
Subject Carboplatin Small molecule 5 unknown Intravenous
Subject Cisplatin Other / unclassified 25 mg/m2 —
Subject Etoposide Small molecule 100 mg/m2 Intravenous
Subject Rivoceranib Small molecule 250 mg Oral