drugset / Trial / NCT05171049

A Study Comparing Abelacimab to Apixaban in the Treatment of Cancer-associated VTE

NCT05171049

RandomizedParallel-groupSingle-blindTreatment

Summary

This is a Phase 3,multicenter, randomized, open-label, blinded endpoint evaluation study comparing the effect of abelacimab relative to apixaban on venous thromboembolism (VTE) recurrence and bleeding in patients with cancer associated VTE (ASTER)

Timeline

Start
2022-05-05
Primary completion
2026-02-04
Completion
2026-02-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Abelacimab Monoclonal antibody 150 mg Intravenous
Comparator Apixaban Small molecule 5 mg Oral