drugset / Trial / NCT05178654
Study to Investigate the Mass Balance, Metabolism, and Excretion of [14C]PF-07321332 in Healthy Male Participants.
RandomizedSingle-groupOpen-labelBasic science
Summary
This study is to characterize mass balance and further the understanding of human pharmacokinetics, metabolism, and excretion of radiolabeled \[14C\]PF-07321332 in healthy male participants following oral administration with ritonavir.
Timeline
- Start
- 2022-02-22
- Primary completion
- 2022-04-01
- Completion
- 2022-04-01
Outcome
Outcome not reported
Stopped: “Based on various healthy authorities feedback on PAXLOVID submission, this study is no longer required.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nirmatrelvir | Small molecule | 100 unknown | Oral |
| Subject | Nirmatrelvir | Small molecule | 300 mg | Oral |
| Background | Ritonavir | Other / unclassified | 100 mg | — |
Indications
No indication recorded.