drugset / Trial / NCT05188339
The Effectiveness and Safety of 4% Sodium Citrate as a Lock Solution in Central Venous Hemodialysis Catheter
Non-randomizedParallel-groupOpen-labelPrevention
Summary
Studies that used a dilute citrate formulation (4%) demonstrated efficacy as an anticoagulant with minimal to no risk of bleeding in HD sessions. This study will compare effectiveness and safety utilizing 4% sodium citrate vs. heparin as a lock solution in central venous hemodialysis catheter among hemodialysis patients.
Timeline
- Start
- 2022-07-20
- Primary completion
- 2022-12-31
- Completion
- 2022-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Heparin | Other / unclassified | 8000 iu | Other |
| Comparator | Heparin | Other / unclassified | 9000 iu | Other |
| Subject | sodium citrate | Unknown | 4 % | Other |