drugset / Trial / NCT05189977
A Trial to Assess the Effects of Prazosin or Propranolol on Blood Pressure in the Presence of Brexpiprazole/Sertraline
Phase 1
Terminated
34 enrolled
Otsuka Pharmaceutical Development & Commercialization, Inc.
IQVIA Pty Ltd · collab
Non-randomizedCrossoverOpen-labelOther
Summary
A Trial to Assess the Effects of Prazosin or Propranolol on Blood Pressure in the Presence of Brexpiprazole/Sertraline
Timeline
- Start
- 2022-09-07
- Primary completion
- 2023-08-03
- Completion
- 2023-08-03
Outcome
Outcome not reported
Stopped: “The decision to terminate the trial early was not based on safety concerns. The trial was terminated early due to some implausible blood pressure values being captured, which was the primary endpoint of the study.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Prazosin | Unknown | 1 mg | Oral |
| Comparator | Propranolol | Small molecule | 40 mg | Oral |