drugset / Trial / NCT05191875

Saccharomyces Boulardii as Pretreatment Before Rescue Therapy of Helicobacter Pylori

NCT05191875

RandomizedParallel-groupOpen-labelTreatment

Summary

The increasing rate of drug resistance in often leads to eradication failure and the need for rescue therapy, and it is of great significance to explore new rescue therapeutic regimens. In this study, we observed the efficacy of rescue treatment of Helicobacter pylori (H.pylori) with Saccharomyces boulardii (S.boulardii) alone. the primary outcome of the trial was the eradication rate, and the secondary outcome was the incidence of adverse events.

Timeline

Start
2021-12-01
Primary completion
2022-04-12
Completion
2022-04-23

Drugs

EvaluationDrugModalityDoseRoute
Subject Saccharomyces boulardii Other / unclassified 500 mg
Background Doxycycline Small molecule 0.1 g
Background Furazolidone Small molecule 0.1 g
Background Ilaprazole Small molecule 5 mg
Background colloidal bismuth tartrate Unknown 220 mg