drugset / Trial / NCT05191875
Saccharomyces Boulardii as Pretreatment Before Rescue Therapy of Helicobacter Pylori
RandomizedParallel-groupOpen-labelTreatment
Summary
The increasing rate of drug resistance in often leads to eradication failure and the need for rescue therapy, and it is of great significance to explore new rescue therapeutic regimens. In this study, we observed the efficacy of rescue treatment of Helicobacter pylori (H.pylori) with Saccharomyces boulardii (S.boulardii) alone. the primary outcome of the trial was the eradication rate, and the secondary outcome was the incidence of adverse events.
Timeline
- Start
- 2021-12-01
- Primary completion
- 2022-04-12
- Completion
- 2022-04-23
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Saccharomyces boulardii | Other / unclassified | 500 mg | — |
| Background | Doxycycline | Small molecule | 0.1 g | — |
| Background | Furazolidone | Small molecule | 0.1 g | — |
| Background | Ilaprazole | Small molecule | 5 mg | — |
| Background | colloidal bismuth tartrate | Unknown | 220 mg | — |