drugset / Trial / NCT05215834

The Comparison of Remimazolam With Propofol in Core Body Temperature

NCT05215834 ↗

Phase 4 Completed 90 enrolled Wonkwang University Hospital
RandomizedParallel-groupOpen-labelScreening

Summary

1. Core body temperature is normally tightly regulated to within a few tenths of a degree. The major thermoregulatory defences in humans are sweating, arteriovenous shunt vasoconstriction, and shivering. 2. Inadvertent hypothermia often complicates prolonged surgery. In patients becoming sufficiently hypothermic, reemergence of thermoregulatory vasoconstriction usually prevents further core hypothermia. 3. The extent to which anesthetics reduce the vasoconstriction threshold depends on the type of drug and its concentration.

Timeline

Start
2021-03-01
Primary completion
2021-06-30
Completion
2021-11-30

Drugs

EvaluationDrugModalityDoseRoute
Background Remifentanil Small molecule 3 ng/ml Intravenous

Indications

No indication recorded.