drugset / Trial / NCT05216822

Anti-Secretory Drug in Treatment of Acute Watery Diarrhea

NCT05216822 ↗

Phase 1 Completed 50 enrolled Assiut University
RandomizedParallel-groupDouble-blindTreatment

Summary

In conclusion, racecadotril is an anti-secretory drug that exerts its antidiarrheal effect by inhibiting intestinal enkephalinase. It is effective in reducing the volume and frequency of stool output. racecadotril is well tolerated and safe by providing symptomatic relief and reducing the severity of diarrhea as an adjuvant therapy during the acute attack of gastroenteritis. It is recommended that the new generations of already discovered drugs for control of secretory diarrhea should be studied to discover the ones with fewer side effects to other systems in the body.

Timeline

Start
2018-06-01
Primary completion
2018-07-31
Completion
2018-08-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Racecadotril Small molecule 1.5 mg/kg Oral

Indications