The Antibacterial Effect of Nanosilver Fluoride on Primary Teeth

Summary

To assess the antibacterial effect of Nanosilver Fluoride (NSF) in relation to caries activity in dentin caries lesions of primary teeth in comparison to Silver Diamine Fluoride (SDF).

Timeline

Start

2022-03-15

Primary completion

2022-04-15

Completion

2022-06-15

Outcome

Outcome not reported

Stopped: “Only the 1 month follow-up was completed. The principal investigator could not complete the 3 month follow-up appointments and was not calibrated with other dentists who were available at the time.”

Publications

• Ammar N, El-Tekeya MM, Talat DM, Essa S, Essawy MM, Kuhnisch J, Hamed H, Nabil N, Achy SE, Tantawi ME. Effect of silver diamine fluoride and nanosilver on salivary bacterial counts in children with early childhood caries: a randomized controlled clinical trial. BMC Oral Health. 2025 Jun 9;25(1):945. doi: 10.1186/s12903-025-06325-3.
• Ammar N, El-Tekeya MM, Essa S, Essawy MM, Talaat DM. Antibacterial effect and impact on caries activity of nanosilver fluoride and silver diamine fluoride in dentin caries of primary teeth: a randomized controlled clinical trial. BMC Oral Health. 2022 Dec 30;22(1):657. doi: 10.1186/s12903-022-02697-y.
• Ammar N, El-Tekeya MM, Essa S, Essawy MM, El Achy SN, Talaat DM. The antibacterial effect of nanosilver fluoride in relation to caries activity in primary teeth: a protocol for a randomized controlled clinical trial. Trials. 2022 Jul 8;23(1):558. doi: 10.1186/s13063-022-06477-5.

Drugs

Indications