drugset / Trial / NCT05232357

Endoscopic Vital Nerve Staining in Gastrointestinal Diseases

NCT05232357

NaSingle-groupOpen-labelDiagnostic

Summary

In this study, methylene blue (MB) was used as vital nerve staining agent. During gastroenteroscopy, mucosal nerve staining was achieved by endoscopic submucosal injection of MB solution. To observe the staining of nerve fibers, neurons and glial cells in mucosa and submucosa, as well as the morphological changes, density differences and function of mucosal nerve tissues in different gastrointestinal lesions, in order to explore the role of endoscopic vital nerve staining in the diagnosis of gastrointestinal lesions.

Timeline

Start
2022-03-01
Primary completion
2022-05-01
Completion
2022-05-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Methylene Blue Diagnostic / imaging agent 20 mg Topical
Background Sodium Thiosulfate Diagnostic / imaging agent 800 mg Topical