drugset / Trial / NCT05232357
Endoscopic Vital Nerve Staining in Gastrointestinal Diseases
NaSingle-groupOpen-labelDiagnostic
Summary
In this study, methylene blue (MB) was used as vital nerve staining agent. During gastroenteroscopy, mucosal nerve staining was achieved by endoscopic submucosal injection of MB solution. To observe the staining of nerve fibers, neurons and glial cells in mucosa and submucosa, as well as the morphological changes, density differences and function of mucosal nerve tissues in different gastrointestinal lesions, in order to explore the role of endoscopic vital nerve staining in the diagnosis of gastrointestinal lesions.
Timeline
- Start
- 2022-03-01
- Primary completion
- 2022-05-01
- Completion
- 2022-05-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methylene Blue | Diagnostic / imaging agent | 20 mg | Topical |
| Background | Sodium Thiosulfate | Diagnostic / imaging agent | 800 mg | Topical |